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Multiple Choice

A potential complication of cryptorchidism is which of the following?

Undescended testes sit in a warmer environment, which disrupts normal germ cell development and can lead to infertility. But the more clinically important and well-established complication is an increased risk of malignant transformation in the testis, particularly if the testis remains undescended (intra-abdominal or inguinal). This cancer risk persists even after corrective surgery in many cases, though early orchiopexy can reduce some risk by allowing better surveillance and, to some extent, normalizing temperature exposure. Among the options, the increased risk of malignancy best captures a recognized long-term complication of cryptorchidism. The other statements don’t fit as well: infertility can occur but isn’t the sole issue, infection risk isn’t decreased, and there are real long-term risks rather than none.

Undescended testes sit in a warmer environment, which disrupts normal germ cell development and can lead to infertility. But the more clinically important and well-established complication is an increased risk of malignant transformation in the testis, particularly if the testis remains undescended (intra-abdominal or inguinal). This cancer risk persists even after corrective surgery in many cases, though early orchiopexy can reduce some risk by allowing better surveillance and, to some extent, normalizing temperature exposure. Among the options, the increased risk of malignancy best captures a recognized long-term complication of cryptorchidism. The other statements don’t fit as well: infertility can occur but isn’t the sole issue, infection risk isn’t decreased, and there are real long-term risks rather than none.