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Multiple Choice

PSA elevation can occur with which of the following conditions?

PSA elevation happens when any process increases PSA production or leakage from the prostate into the bloodstream. In benign prostatic hyperplasia, the enlarged gland has more PSA-secreting tissue, so total PSA rises even without cancer. In prostatitis, inflammation or infection irritates the gland and disrupts barriers, allowing more PSA to enter the circulation. In prostate cancer, malignant cells keep producing PSA and the tumor disrupts normal tissue, further increasing PSA levels. Because PSA can rise with growth, inflammation, or malignancy of the prostate, an elevated PSA can occur with all of the above.

PSA elevation happens when any process increases PSA production or leakage from the prostate into the bloodstream. In benign prostatic hyperplasia, the enlarged gland has more PSA-secreting tissue, so total PSA rises even without cancer. In prostatitis, inflammation or infection irritates the gland and disrupts barriers, allowing more PSA to enter the circulation. In prostate cancer, malignant cells keep producing PSA and the tumor disrupts normal tissue, further increasing PSA levels. Because PSA can rise with growth, inflammation, or malignancy of the prostate, an elevated PSA can occur with all of the above.