Which prostate zone is most commonly involved in BPH?

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Multiple Choice

Which prostate zone is most commonly involved in BPH?

The change most associated with BPH occurs in the transitional zone, the inner part of the prostate that surrounds the prostatic urethra. As men age, hyperplastic nodules develop here and expand around the urethra, often causing bladder outlet obstruction and urinary symptoms. The central zone and peripheral zone are anatomically distinct and not the usual sites for BPH; the peripheral zone is where most prostate cancers arise, while the central zone is less commonly involved in benign enlargement. The anterior fibromuscular stroma consists mostly of fibrous and muscular tissue with little glandular tissue, so it doesn’t drive the typical hyperplasia seen in BPH.

The change most associated with BPH occurs in the transitional zone, the inner part of the prostate that surrounds the prostatic urethra. As men age, hyperplastic nodules develop here and expand around the urethra, often causing bladder outlet obstruction and urinary symptoms. The central zone and peripheral zone are anatomically distinct and not the usual sites for BPH; the peripheral zone is where most prostate cancers arise, while the central zone is less commonly involved in benign enlargement. The anterior fibromuscular stroma consists mostly of fibrous and muscular tissue with little glandular tissue, so it doesn’t drive the typical hyperplasia seen in BPH.

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